中文名称：帕瑞肽
目录号：P1127
Pasireotide (SOM230)是一种多受体配体生长抑素类似物，对生长抑素受体 (somatostatin receptor, SSTR)亚型 sst1、2、3 和sst5具有高结合亲和力。 它能有效抑制GH、IGF-I和ACTH分泌，表明其对肢端肥大症和库欣氏病具有潜在疗效。
Amino-acid Sequence
CAS: 396091-73-9
| 批次： P112701 DMSO] 100 mg/mL] false] Ethanol] 100 mg/mL] false] Water] Insoluble] false | 纯度： 99.47% |
| 储存条件(自收到货起) | 3年 -20°C 粉状 |
建议分装储备液，避免反复冻融！ |
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| 体外溶解度 | 批次： |
|
DMSO : 100 mg/mL ( 95.49 mM； DMSO吸湿会降低化合物溶解度，请使用新开封DMSO) Ethanol : 100 mg/mL Water : Insoluble |
|
| 体内溶解度 | 批次： |
| 现配现用，请按从左到右的顺序依次添加，澄清后再加入下一溶剂 | |
| Molecular Formula: | C58H66N10O9 |
|---|---|
| Molecular Weight: | 1047.21 |
| CAS No.: | 396091-73-9 |
| Appearance: | White Powder |
| Peptide Content(by %N): | ≥80% |
| Water Content(Karl Fischer): | ≤5.0% |
| Amino Acid Composition: | ±10% of theoretical |
| Single Impurity(by HPLC): | ≤1.0% |
| Assay(By Anhydrous, Acetic Acid-free): | 95.0~105.0% |
| Bacterial Endotoxins: | ≤1EU/mg |
| ldentity by HPLC: | 100 |
| MS: | Consistent |
| Packing: | plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement. |
| Storage: | 3 years-20°C powder |
