目录号：P1220
Tat-NR2B9c (Tat-NR2Bct，NA-1)是一种突触后密度蛋白-95(postsynaptic density-95, PSD-95)抑制剂，对PSD-95d2 (PSD-95 PDZ域2)和PSD-95d1的EC50值分别6.7 nM和670 nM，Tat-NR2B9c (Tat-NR2Bct，NA-1)能破坏PSD-95/NMDAR相互作用，抑制NR2A及NR2B与PSD-95结合的IC50分别为0.5 μM和8 μM，同时抑制神经元一氧化氮合酶（neuronal nitric oxide synthase，nNOS）与PSD-95的相互作用，具有神经保护作用。
Amino-acid Sequence
CAS: 500992-11-0
| 批次： P122001 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] Insoluble] false | 纯度： 98.02% |
| 储存条件(自收到货起) | 3年 -20°C 粉状 |
建议分装储备液，避免反复冻融！ |
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| 体外溶解度 | 批次： |
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DMSO : 100 mg/mL ( 39.7 mM； DMSO吸湿会降低化合物溶解度，请使用新开封DMSO) Water : 100 mg/mL Ethanol : Insoluble |
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| 体内溶解度 | 批次： |
| 现配现用，请按从左到右的顺序依次添加，澄清后再加入下一溶剂 | |
| Molecular Formula: | C105H188N42O30 |
|---|---|
| Molecular Weight: | 2518.88 |
| CAS No.: | 500992-11-0 |
| Appearance: | White Powder |
| Peptide Content(by %N): | ≥80% |
| Water Content(Karl Fischer): | ≤5.0% |
| Amino Acid Composition: | ±10% of theoretical |
| Single Impurity(by HPLC): | ≤1.0% |
| Assay(By Anhydrous, Acetic Acid-free): | 95.0~105.0% |
| Bacterial Endotoxins: | ≤1EU/mg |
| MS: | Consistent |
| Packing: | plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement. |
| Storage: | 3 years-20°C powder |
