Fer-1 (Ferrostatin-1)
目录号:S7243 Purity: 99.98%
Fer-1 (Ferrostatin-1)是一种有效的选择性的ferroptosis抑制剂,EC50为60 nM。
CAS: 347174-05-4
客户使用Selleck的Fer-1 (Ferrostatin-1)发表文献509篇
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化学信息&溶解度
分子量 | 262.35 |
分子式 | C15H22N2O2 |
CAS号 | 347174-05-4 |
Smiles | CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N |
储存条件(自收到货起) | |
建议分装储备液,避免反复冻融! |
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体外溶解度 | 批次: |
DMSO : 55 mg/mL ( 209.64 mM; DMSO吸湿会降低化合物溶解度,请使用新开封DMSO) Ethanol : 55 mg/mL Water : Insoluble DMSO : 52 mg/mL ( 198.2 mM; DMSO吸湿会降低化合物溶解度,请使用新开封DMSO) Ethanol : 52 mg/mL Water : Insoluble |
体内溶解度 | 批次: |
现配现用,请按从左到右的顺序依次添加,澄清后再加入下一溶剂 | |
5% DMSO
40% PEG 300
5%tween 80
50%ddH2O
浓度:1mg/ml
(3.81mM)
操作示例:以 1 mL 工作液为例,取50μL 20 mg/ml的澄清DMSO储备液加到400μL PEG300中,混合均匀使其澄清;向上述体系中加入50μLTween80,混合均匀使其澄清;然后继续加入500 μL ddH2O定容至 1 mL。工作液请现配现用!
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5%DMSO
40%PEG300
5%Tween80
50%ddH2O
浓度:5mg/ml
(19.06mM)
操作示例:以 1 mL 工作液为例,取50μL100mg/ml的澄清DMSO储备液加到400μLPEG300中,混合均匀使其澄清;向上述体系中加入50μLTween80,混合均匀使其澄清;然后继续加入500μLddH2O定容至1mL。工作液请现配现用!
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2% DMSO
50% PEG 300
5% Tween 80
ddH2O
浓度:1mg/ml
(3.81mM)
操作示例:以 1 mL 工作液为例,取20 μL 50 mg/ml的澄清DMSO储备液加到500 μL PEG300中,混合均匀使其澄清;向上述体系中加入50 μL Tween-80,混合均匀使其澄清;然后继续加入430 μL ddH2O定容至 1 mL。工作液请现配现用!
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5% DMSO
95% Corn oil
浓度:1.65mg/ml
(6.29mM)
操作示例:以1 mL工作液为例,取50μL 33mg/ml的澄清DMSO储备液加到950μL玉米油中,混合均匀。工作液请现配现用!
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摩尔浓度计算器
质量(g)= 浓度(mol/L)* 体积(L)* 分子量(g/mol)
动物体内配方计算器(澄清溶液)
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,注:如该浓度超过该批次药物DMSO溶解度,请先联系Selleck);
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入 μL Tween 80,混匀澄清后加入 μL ddH2O,混匀澄清。
体内配方配制方法:取 μL DMSO母液,加入 μL Corn oil,混匀澄清。
注意:
1. 首先保证母液是澄清的;
2.一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。