细胞死亡
- 细胞凋亡 [1]
-
- Bcl-2 Family
- Venetoclax
- Navitoclax
- ABT-737
- S63845
- AZD5991
- TW-37
- Sabutoclax
- BDA-366
- Obatoclax
-
- MDM-2/p53
- Nutlin-3a
- Idasanutlin
- Triptolide
- RG-7112
- -Parthenolide
- NVP-CGM097
- 坏死性凋亡 [2]
-
- HSP90
- Tamoxifen
- Tamoxifen Citrate
- 细胞焦亡 [3]
-
- Caspase-1
- Belnacasan
- Z-YVAD-FMK
- Mulberroside A
- Chelidonic acid
-
- GSDMD
- Ac-FLTD-CMK
- Disulfiram
- LDC7559
- 2-BP
-
- Caspase-4/5/11
- Belnacasan
- Ac-FLTD-CMK
- Wedelolactone
- 自噬 [4]
-
- Beclin/Vps34 Complex
- LY294002
- Wortmannin
- 3-MA
- Spautin-1
-
- ATG4B
- NSC 185058
-
- PI3K Complex抑制剂
- LY294002
- Wortmannin
- Pictilisib
- Buparlisib
-
- p110δ抑制剂
- Idelalisib
- P110δ-IN-1
- acalisib
- IPI-3063
- 铁死亡 [5]
- 铜死亡 [6]
-
- 辅助因子
- -α-Lipoic acid
-
- FDX1
- Elesclomol
-
- ATP7B
- tetrathiomolybdate
- 双硫死亡 [7]
-
- SLC7A11/xCT
- HG106
- Levobupivacaine
- Anti-CD98
-
- 硫醇氧化剂
- Diethylmaleate
- 相关化合物库
- Apoptosis Compound Library
- Autophagy Compound Library
- Ferroptosis Compound Library
- Pyroptosis Compound Library
- Mitochondria-Targeted Compound Library
- Oxidative Stress Compound Library
参考文献
- [1] Pistritto G, et al. Aging (Albany NY). 2016 Mar 27; 8:603-619.
- [2] Grootjans S, et al. Cell Death Differ. 2017 Jul;24(7):1184-1195.
- [3] Fang Y, et al. Biomed Pharmacother. 2020 Jan;121:109595.
- [4] Levy JMM, et al. Nat Rev Cancer. 2017 Sep;17(9):528-542.
- [5] Tang D, et al. Cell Res. 2021 Feb;31(2):107-125.
- [6] Xie J, et al. Mol Cancer. 2023 Mar 7;22(1):46.
- [7] Liu X, et al. Nat Cell Biol. 2023 Mar;25(3):404-414.
